Comprehensive Treatment of Obstructive Hypertrophic Cardiomyopathy

pp 82-83

Abstract

Obstructive hypertrophic cardiomyopathy is a cardiac
condition characterized by ventricular hypertrophy
and a progressive worsening of symptoms associated
to increased subaortic gradient. Pharmacological
treatment with negative inotropic agents usually relieves
symptomatology and functional capacity. When
symptoms do not subside, which occurs in 5% of the
patients, an invasive behavior must be established, either
with surgical septal myectomy, initiated by Morrov
in 1968, (1) or alcohol septal ablation. This last
method was introduced by Sigwart in 1995 in three
patients to provoke hypokinesia (controlled infarction)
in the area with consequent gradient reduction.