Compromiso cardíaco y su relación con la gravedad del cuadro  agudo y los síntomas persistentes en la convalecencia de infección  por COVID-19 : pp. 332-339

Josefina B. Parodi; Pamela Bobadilla Jacob; Guillermo C. Toledo; Rubén G. Micali; Mercedes P. Iacino; Belén Sotelo; Cecilia Bruno; María Pelletier; Walter Masson Juárez; Melina S. Huerin

doi:10.7775/rac.es.v89.i4.20426

Authors

Josefina B. Parodi Instituto Cardiovascular Lezica https://orcid.org/0000-0003-3092-7045
Pamela Bobadilla Jacob Instituto Cardiovascular Lezica https://orcid.org/0000-0001-7169-5135
Guillermo C. Toledo In https://orcid.org/0000-0001-5665-2225
Rubén G. Micali Ins https://orcid.org/0000-0001-7440-1091
Mercedes P. Iacino Instituto Cardiovascular Lezica https://orcid.org/0000-0002-5171-1326
Belén Sotelo Instituto Cardiovascular Lezica https://orcid.org/0000-0001-8363-871X
Cecilia Bruno Instituto Cardiovascular Lezica https://orcid.org/0000-0003-2397-9461
María Pelletier Instituto Cardiovascular Lezica https://orcid.org/0000-0002-3009-9086
Walter Masson Juárez Instituto Cardiovascular Lezica https://orcid.org/0000-0002-5620-6468
Melina S. Huerin Instituto Cardiovascular Lezica https://orcid.org/0000-0002-9398-1463

DOI:

https://doi.org/10.7775/rac.es.v89.i4.20426

Keywords:

COVID-19/complications, SARS-CoV-2, Myocarditis, Cardiomyopathy, Echocardiography

Abstract

Background: The acute phase of COVID-19 infection is associated with cardiovascular involvement, but there is limited information regarding this relationship in the recovery phase from this disease both in patients with or without persistent symptoms.

Objectives: The aims of this study were: 1. To analyze cardiovascular involvement by echocardiography in the recovery phase from COVID-19 disease, and 2. To explore its association with: a) the severity of the acute phase and b) the presence of persistent symptoms.

Methods: An analytical, observational, prospective and single-center study was carried out, including consecutive patients attending
the center for post-COVID-19 evaluation who underwent a transthoracic color Doppler echocardiogram looking for pathological outcomes.

Results: A total of 600 patients were included from September 1, 2020 to May 1, 2021, and 29 of these patients (4.8%) presented pathological findings in the echocardiogram. Patients with moderate or severe acute phase COVID-19 infection had a higher prevalence of wall motion disorders (4.3% vs. 0.5%, p=0.02) and pericardial effusion (4.3% vs. 0.24%, p=0.01) compared with those with
asymptomatic or mild symptoms; however, after multivariate adjustment, this association did not reach statistical significance. In 28.6% of cases, patients reported persistent symptoms, with no evident association between their presence and pathological echocardiographic results.

Conclusion: The prevalence of cardiovascular involvement evaluated by echocardiography was 4.8% in the recovery phase from COVID-19 disease. Patients with more severe initial clinical presentation exhibited more pathological findings, but the significance was not sustained in the multivariate analysis. Persistent symptoms were not associated with greater cardiovascular involvement.

How to cite this article:

Parodi JB.Cardiovascular Involvement and its Relationship with the Severity of the Acute Phase and Persistent Symptoms during Recovery from COVID-19 Infection. REV ARGENT CARDIOL 2021;89:321-327.

http://dx.doi.org/10.7775/rac.v89.i4.20426