Weekly Distribution of Acute Coronary Syndrome. Analysis of the Epi-Cardio Registry

pp. 547-550

Abstract

Background: Acute coronary syndromes (ACS) seem to have a chronobiological distribution with seasonal, weekly and circadian variations. So far, there is no evidence in the published literature about the weekly distribution of ACS in Argentina; thus, it is unknown whether ACS have a specific pattern and which could be the associated variables.
Objective: The aim of this study was to analyze the weekly distribution of ACS and the differences in treatment and clinical outcome.
Methods: The distribution of non-ST-segment elevation (NSTE) (n=6,277) and ST-segment elevation (STE) ACS (n=4,237) was retrospectively analyzed according to the day of the week using the 2006-2012 Epi-Cardio registry.
Results: The frequency was higher during the first days of the week and descended during the weekend (overall ACS and NSTE-ACS p <0.001, and STE-ACS p <0.01), and was not related to either age or sex. In STE-ACS, the indication and the type of reperfusion therapy did not present differences according to the day of the week.
Conclusions: The frequency of hospitalization due to ACS is higher within the first weekdays and decreases during the weekend, with no differences in the use of complex resources or in the initial outcome.